Technology Record - Issue 40: Spring 2026

65 artworks, expanding access and engagement while preserving the integrity of the in-person encounter. Healthcare is another domain where AI for social impact goes far beyond efficiency. We are involved in experimental research on biological computing in collaboration with the University of Milan, exploring how living neural systems can interact with computational platforms to open new frontiers in medical and scientific research. At the same time, AI is already delivering concrete benefits in clinical practice. We have applied AI-driven systems to mammography screening at the European Institute of Oncology, supporting radiologists in prioritising cases, improving diagnostic workflows and reducing waiting times while keeping human expertise firmly in control. Beyond clinical settings, digital and datadriven platforms are strengthening prevention, safety and trust across healthcare ecosystems. In the UK, Reply contributed to the development of a drug overdose prevention app leveraging Azure Cloud services, to empower communities with life-saving tools and timely information. In parallel, we have played a key role in implementing systems verifying medicines across Europe, helping to combat counterfeit drugs and protect patient safety. Together, these initiatives show how data, platforms and intelligent systems can strengthen public health outcomes at scale. Across all these scenarios, a common pattern emerges. AI for social impact rarely succeeds as a standalone initiative. The most effective projects are built within ecosystems that combine technology platforms, domain expertise and integration capabilities. Ultimately, the success of AI for social impact should not be measured by innovation narratives, but by outcomes. Organisations are increasingly shifting from return on investment to return on mission: improvements in service quality, accessibility, safety and long-term sustainability. This is where AI, when grounded in execution and trust, can make a meaningful difference. Richard Acreman is an executive partner for Reply Reply worked with Microsoft and Iconem to create a digital twin of St. Peter’s Basilica in Vatican City Image: Microsoft and Iconem

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